All::Endocrinology::Pharmacology::Meglitinides

Intro

What is the drug class of repaglinide, nateglinide?

Meglitinides

What is the method of action of Meglitinides?

they bind to an ATP-dependent K+(KATP) channel on the cell membrane of pancreatic beta cells

What is the main clinical use of Meglitinides?

increase pancreatic insulin secretion

often used for patients with an erratic lifestyle

What are the main adverse effects of Meglitinides?

weight gain and hypoglycaemia (less so than sulfonylureas)