All::Clinical Science::Statistics::Sensitivity and Specificity

Intro

What is meant by Sensitivity of a test?

Proportion of patients with the condition who have a positive test result

How is Sensitivity calculated?

TP / (TP + FN)

What is meant by Specificity of a test?

Proportion of patients without the condition who have a negative test result

How is Specificity calculated?

TN / (TN + FP)

What is meant by a tests Positive predictive value?

The chance that the patient has the condition if the diagnostic test is positive

How do you calculate Positive predictive value?

TP / (TP + FP)

What is meant by a tests Negative predictive value?

The chance that the patient does not have the condition if the diagnostic test is negative

How do you calculate Negative predictive value?

TN / (TN + FN)

What is meant by a tests Likelihood ratio for a positive test result?

How much the odds of the disease increase when a test is positive

How do you calculate a Likelihood ratio for a positive test result?

sensitivity / (1 - specificity)

What is meant by a tests Likelihood ratio for a negative test result?

How much the odds of the disease decrease when a test is negative

How do you calculate a Likelihood ratio for a negative test result?

(1 - sensitivity) / specificity