All::Neurology::Diseases::Neurological findings::Internuclear ophthalmoplegia

Intro

What are the main clinical features of Internuclear ophthalmoplegia?

  • impaired adduction of the eye on the same side as the lesion
  • horizontal nystagmus of the abducting eye on the contralateral side

Where is the lesion that causes Internuclear ophthalmoplegia?

a lesion in the medial longitudinal fasciculus (MLF)

What is the pathophysiology of Internuclear ophthalmoplegia?

medial longitudinal fasciculus controls horizontal eye movements by interconnecting the IIIrd, IVth and VIth cranial nuclei

What are the causes of Internuclear ophthalmoplegia?

  • multiple sclerosis
  • vascular disease