All::Neurology::Diseases::Subacute combined degeneration of the spinal cord
Intro
What are the main clinical features of Subacute combined degeneration of the spinal cord?
weakness of the legs, arms, and trunk, and tingling and numbness that progressively worsens. Vision changes and change of mental state may also be present
What is the pathophysiology of Subacute combined degeneration of the spinal cord?
due to vitamin B12 deficiency resulting in impairment of the dorsal columns, lateral corticospinal tracts and spinocerebellar tracts
What are the main associations of Subacute combined degeneration of the spinal cord?
pernicious anemia