What is Fanconi syndrome?

a syndrome of inadequate reabsorption in the proximal renal tubules

What are the main clinical features of Fanconi syndrome?

• type 2 (proximal) renal tubular acidosis
• polyuria
• aminoaciduria
• glycosuria
• phosphaturia
• osteomalacia

What are the main causes of Fanconi syndrome?

• cystinosis (most common cause in children)
• Sjogren's syndrome
• multiple myeloma
• nephrotic syndrome
• Wilson's disease