All::Gastroenterology::Diseases::Cyclical vomiting syndrome

Intro

What is cyclical vomiting syndrome?

Chronic functional condition of unknown pathogenesis, characterized by recurring vomiting episodes.

What is the epidemiology of cyclical vomiting syndrome?

Rare, more common in children than adults, slightly more affected in females than males.

What percentage of children and adults with cyclical vomiting syndrome also have migraines?

80% of children, 25% of adults.

What are the typical presentations of cyclical vomiting syndrome?

Severe nausea, sudden vomiting lasting hours to days, prodromal intense sweating and nausea, well in between episodes.

What symptoms may be present alongside vomiting in cyclical vomiting syndrome?

Weight loss, reduced appetite, abdominal pain, diarrhea, dizziness, photophobia, headache.

What investigations are typically done for cyclical vomiting syndrome?

Clinical diagnosis, pregnancy test in women, routine blood tests.

What management strategies are recommended for cyclical vomiting syndrome?

Avoidance of triggers, prophylactic treatments like amitriptyline, propranolol, and topiramate, ondansetron, prochlorperazine, and triptans in acute episodes.