What is the drug class of Allopurinol?

xanthine oxidase inhibitor

What is the method of action of Allopurinol?

• Allopurinol is a xanthine oxidase inhibitor.
• Xanthine oxidase metabolises xanthine (produced from purines) to uric acid

What is the main clinical use of Allopurinol?

• Prevent acute attacks of gout
• Prevent uric acid and calcium oxalate renal stones
• Prevent hyperuricaemia and tumour lysis syndrome associated with chemotherapy

What are the main drug interaction of Allopurinol?

Azathioprine require xanthine oxidase for metabolism, so Allopurinol will increase risk of toxicity