All::Cardiovascular System::Pharmacology::Alpha-blockers
Intro
What is the method of action of Alpha-blockers?
- Most alpha blockers are highly selective for the α1-adrenoceptor
- α1 causes smooth muscle contraction (mainly in bladder and blood vessels)
What is the main clinical use of Alpha-blockers?
- symptoms in benign prostatic hyperplasia
- resistant hypertension, when other medicines are insufficient
What are the main adverse effects of Alpha-blockers?
- postural hypotension
- dizziness
- syncope