What is the method of action of Histamine H1-receptor antagonists?

Histamine (H1) and acetylcholine (muscarinic) receptors predominate in the vomiting centre and in its communication with the vestibular system

What is the main clinical use of Histamine H1-receptor antagonists?

Nausea and vomiting, particularly in the context of motion sickness or vertigo

What are the main adverse effects of Histamine H1-receptor antagonists?

• Drowsiness
• Dry throat and mouth

What is an example of Histamine H1-receptor antagonists?

cyclizine