All::Cardiovascular System::Diseases::Acute pericarditis

Intro

Acute pericarditis is a condition referring to inflammation of the {{c1::pericardial sac}}

Aetiology

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What are the infective causes of Acute pericarditis?

  • viral infections (Coxsackie)
  • tuberculosis

Acute pericarditis post MI early (1-3 days): {{c1::fibrinous pericarditis}} late (weeks to months): {{c2::autoimmune pericarditis Dresslers syndrome}}

Which connective tissue disease can cause Acute pericarditis?

  • systemic lupus erythematosus
  • rheumatoid arthritis

What malignancies can cause Acute pericarditis?

  • lung cancer
  • breast cancer

General

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What are the features of Acute pericarditis?

  • chest pain: may be pleuritic. Is often relieved by sitting forwards
  • other symptoms include a non-productive cough, dyspnoea and flu-like symptoms
  • pericardial rub

What ECG changes are seen in Acute pericarditis?

  • the changes in pericarditis are often global/widespread, as opposed to the 'territories' seen in ischaemic events
  • 'saddle-shaped' ST elevation
  • PR depression: most specific ECG marker for pericarditis

all patients with suspected acute pericarditis should have {{c1::transthoracic echocardiography::?imaging}}

Why is troponin checked in Acute pericarditis?

around 30% of patients may have an elevated troponin - this indicates possible myopericarditis

the majority of patients with Acute pericarditis can be managed as {{c1::outpatients::IP/OP}}

Whats the treatment of Acute pericarditis?

  • treat any underlying cause
  • most patients however will have pericarditis secondary to viral infection, meaning no specific treatment is indicated
  • a combination of NSAIDs and colchicine is now generally used for first-line for patients with acute idiopathic or viral pericarditis
  • until symptom resolution and normalisation of inflammatory markers (usually 1-2 weeks) followed by tapering of dose recommended over