All::Cardiovascular System::Pharmacology::Ivabradine

Intro

What is Ivabradine?

a class of anti-anginal drug which works by reducing the heart rate

What is the clinical use of Ivabradine?

to prevent angina pain and heart failure

What is the MOA of Ivabradine?

acts on the If ('funny') ion current which is highly expressed in the sinoatrial node, reducing cardiac pacemaker activity.

What are the main Adverse effects of Ivabradine?

  • visual effects, particular luminous phenomena, are common
  • headache
  • bradycardia, heart block