All::Cardiovascular System::Pharmacology::Nicorandil
Intro
What is the drug class of Nicorandil
An anti-anginal medicine (a potassium-channel activator)
What is the method of action of Nicorandil
a potassium-channel activator with vasodilation is through activation of guanylyl cyclase which results in increase cGMP
What is the main clinical use of Nicorandil
to treat angina
What is the main adverse effects of Nicorandil
- headache
- flushing
- skin, mucosal and eye ulceration
- gastrointestinal ulcers including anal ulceration
What is the main contraindications of Nicorandil
left ventricular failure