All::Oncology::Pharmacology::Tamoxifen

Intro

What is the drug class of Tamoxifen

Selective oEstrogen Receptor Modulators (SERM)

What is the main clinical use of Tamoxifen

management of oestrogen receptor-positive breast cancer

What is the main adverse effects of Tamoxifen

  • menstrual disturbance: vaginal bleeding, amenorrhoea
  • hot flushes - 3% of patients stop taking tamoxifen due to climacteric side-effects
  • venous thromboembolism
  • endometrial cancer