What cell surface proteins associated with Haematopoietic stem cells?

CD34

What cell surface proteins associated with Helper T cell?

CD4, TCR, CD3, CD28

What cell surface proteins associated with Cytotoxic T cell?

CD8, TCR, CD3, CD28

What cell surface proteins associated with Regulatory T cell?

CD4, CD25, TCR, CD3, CD28

What cell surface proteins associated with B cell?

CD19, CD20, CD40, MHC II, B7

What cell surface proteins associated with Macrophage?

CD14, CD40, MHC II, B7

What cell surface proteins associated with Natural killer cell?

CD16, CD56

What are clusters of differentiation (CD)?

a protocol used for the identification and investigation of cell surface molecules providing targets for immunophenotyping of cells

What is the function of CD1?

MHC molecule that presents lipid molecules

What is the function of CD2?

Found on thymocytes, T cells, and some natural killer cells that acts as a ligand for CD58 and CD59 and is involved in signal transduction and cell adhesion

What is the function of CD3?

The signalling component of the T cell receptor (TCR) complex

What is the function of CD4?

• Found on helper T cells.
• Co-receptor for MHC class II
• Used by HIV to enter T cells

What is the function of CD5?

Found in the majority of mantle cell lymphomas

What is the function of CD8?

• Found on cytotoxic T cells.
• Co-receptor for MHC class I
• Found on a subset of myeloid dendritic cells

What is the function of CD14?

Cell surface marker for macrophages

What is the function of CD15?

Expressed on Reed-Sternberg cells (along with CD30)

What is the function of CD16?

Bind to the Fc portion of IgG antibodies

What is the function of CD21?

Receptor for Epstein-Barr virus

What is the function of CD28?

Interacts with B7 on antigen presenting cell as costimulation signal

What is the function of CD45?

Protein tyrosine phosphatase present on all leucocytes

What is the function of CD56?

Unique marker for natural killer cells

What is the function of CD95?

Acts as the FAS receptor, involved in apoptosis