What are the main clinical features of Botulism?

• patient usually fully conscious with no sensory disturbance
• flaccid paralysis
• diplopia
• ataxia
• bulbar palsy

What is the management of Botulism?

botulism antitoxin and supportive care

What bacteria is the cause of Botulism?

Clostridium botulinum

What is the pathophysiology of Botulism?

produces botulinum toxin, a neurotoxin which irreversibly blocks the release of acetylcholine

What are the main risk factors of Botulism?

may result from eating contaminated food (e.g. tinned) or intravenous drug use