All::Haematology::Diseases::Acute promyelocytic leukaemia

Intro

What is Acute promyelocytic leukaemia?

the M3 subtype of Acute myeloid leukemia

What is the cause of Acute promyelocytic leukaemia?

t(15;17) translocation

What are the features of Acute promyelocytic leukaemia that differ it from AML?

  • presents younger than other types of AML (average = 25 years old)
  • DIC or thrombocytopenia often at presentation
  • good prognosis